Table 8
OTA estimates of Mean Enrollment in Clinical Trials Prior to NDA
1978 to 1983, 1986 to 1990
.
1978-1983
1986-1990
Anti-hypertention drugs
1,791
2,485
Anti-microbial
1,885
3,461
Non-steroidal anti-inflammatory
3,036
3,575
Unweighted Average
2,237
3,174
Source: Chapter 3, page 65, 1993 OTA report, Table 3-8: Mean Enrollment in
Clinical Trials Prior to New Drug Application, 1978-83, 1986-90. 1993, the
Office of Technology Assessment, Pharmaceutical R&D: Costs, Risks, and Rewards,
OTA-H-522, GPO stock #052-003-01315-1, NTIS order #PB93-163376.